Endocrine Abstracts

Introduction: ‘PreDiabetes’ was considered as a categories of increased risk for diabetes on the last ADA recommendations in 2010. The proposed diagnostic criteria include an HbA1c value between 5.7 and 6.4%, impaired fasting glucose (IFG) (100–125 mg/dl) and impaired glucose tolerance (IGT) levels (2-h values in the oral glucose tolerance test (OGTT) of 140 to 199 mg/dl). The HbA1c as new diagnostic criteria may actually increase the number of patients diagnose...

Introduction: Type 1 diabetes mellitus (DM1) is frequently associated with other autoimmune diseases. Among children and adolescents, thyroid disease is the most common autoimmune endocrinopathy. The possibility of occult thyroid disease should be considered at diagnosis and when a patient is assessed at the annual review.Objective: The aim of our study was to determine the prevalence of autoimmune thyroiditis among children and adolescents with type 1 d...

Treatment for osteoporosis in children/adolescents is extremely important not only to improve bone quality but also because, if left untreated, could lead to severe and precocious loss of bone mass. Studies in growth hormone (GH) deficient adults, in turn, have shown that treatment with GH produce bone mass gain and improve the occurrence of both bone formation and reabsorption.The authors present the following case report of a 16 year old Caucasian fema...

Introduction: Primary hyperaldosteronism (PHA) and pheochromocytoma are endocrine causes of secondary arterial hypertension. The association of hyperaldosteronism and pheochromocytoma is rare and the involved mechanisms are poorly understood. Either there is coexistence of the two diseases (pheochromocytoma with PHA) or the pheochromocytoma stimulates the production of aldosterone.Case Report: Male, 54 years old, referred to our department for type 2 dia...

Introduction: About 5% of the adult population has adrenal incidentaloma(AI) and its incidence increases with age. AACE guidelines recommend image and hormonal evaluation during 5 years in non functioning AI. The european’s guidelines advise against repeat evaluation in non-secretory AI that present with <4 cm and had benign features. According to recent studies, the risk of developing clinically relevant hormone secretion is <0.3%, in patients with previous non-f...

Introduction: The quality of life (QoL) of patients with Diabetes has been the subject of several studies worldwide. In Portugal, studies have shown that patients under intensive insulin therapy had worse results in QoL questionnaires. The introduction of interstitial glucose monitoring (IGM) appears to reduce the impact of insulin therapy on QoL.Objective: To assess whether IGM changes the quality of life of patients with diabetes, compared to the asses...

Introduction: Diabetes is a disease with great psychosocial impact and reduced quality of life (QoL), and psychosocial factors seem to be excellent predictors of clinical outcomes.Objective: Assess the relationship between the patient’s perception of diabetes management and its impact on QoL.Methods: Interview of patients with type 1 (T1D) and type 2 diabetes (T2D), using the ‘Appraisal of Diabetes Scale’ (ADS), a qu...

Introduction: Obesity is a multifactorial and chronic disease. Bariatric surgery (BS) is the most effective treatment. A prevalence of 45% of esophagitis and 40%-70% of gastritis after BS has been reported. We analysed the presence of gastroesophageal lesions in patients who underwent BS (By-pass Roux-en-Y(BP) and gastric sleeve(GS)) in our centre.Methods: Patients submitted to BS between 2018-2020 were included. We retrospectively analysed clinical data...

Introduction: Thyroid nodules have a high prevalence in the adult population (20-76%). In 2018, the American College of Radiology proposed an ultrasound classification score of thyroid nodules - Thyroid Imaging Reporting and Data System-TIRADS, with 88% of sensitivity and 49% of specificity to predict malignancy. Since then, several studies report sensitivity values of 70.6-97% and specificity of 30-98%. We pretend to compared TIRADS score with cytologic results based on Bethe...

Introduction: Type 2 diabetes (T2D) is a heterogeneous disease for which causal mechanisms are incompletely understood and subclassification may improve patient management. In the latest assessment of patients with adult-onset diabetes, Ahlqvist and colleagues (2018) defined five new subgroups: an autoimmune form, two severe forms (insulin-deficient and insulin-resistant diabetes) and two mild forms (obesity and age-related diabetes).Objectives:...